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VA Center for Clinical Management Research

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Impact of CCMR Work - Strategies

Guidelines for caring for patients after hospital discharge for sepsis

  • This paper provides guidelines on caring for patients after hospital discharge for sepsis, including: hospital and ICU-based strategies to prevent adverse sequelae after sepsis, post-discharge assessment and treatment of sepsis survivors, and screening for treatable medical conditions. This paper was accompanied by a patient education page on post-sepsis morbidity. Based on this work and the history of sepsis work conducted by Drs. Prescott and Iwashyna, Dr. Prescott has been appointed as co-vice chair of the 2020 Surviving Sepsis Campaign Guidelines, with a plan to stay on to chair the 2024 guidelines, continuing to serve for 2028. The Surviving Sepsis Campaign Guidelines were first published in 2004 and are updated every four years. They provide comprehensive guidelines for the identification and management of sepsis and septic shock. They are jointly sponsored by the US Society for Critical Care Medicine and the European Society of Intensive Care Medicine. The 2012 guidelines have been cited over 8,000 times. This position provides Dr. Prescott with a major opportunity to shape sepsis care throughout the country and across the globe.

Standard definition of sepsis

  • This paper presents a definition of sepsis to facilitate widespread retrospective surveillance using routinely collected data from the electronic health record. This definition is being used by VA's National Center for Patient Safety as the denominator for monitoring the impact of their sepsis Virtual Breakthrough Series. The Centers for Disease Control and Prevention are promoting this definition for surveillance work.